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Plos One : Vlps Displaying a Single L2 Epitope Induce Broadly Cross-neutralizing Antibodies Against Human Papillomavirus, Volume 7

By Chen, Zhiwei

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Book Id: WPLBN0003962338
Format Type: PDF eBook :
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Reproduction Date: 2015

Title: Plos One : Vlps Displaying a Single L2 Epitope Induce Broadly Cross-neutralizing Antibodies Against Human Papillomavirus, Volume 7  
Author: Chen, Zhiwei
Volume: Volume 7
Language: English
Subject: Journals, Science, Medical Science
Collections: Periodicals: Journal and Magazine Collection (Contemporary)
Historic
Publication Date:
Publisher: Plos

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Chen, Z. (n.d.). Plos One : Vlps Displaying a Single L2 Epitope Induce Broadly Cross-neutralizing Antibodies Against Human Papillomavirus, Volume 7. Retrieved from http://kindle.worldlibrary.net/


Description
Description : We show that peptides can be displayed in a highly immunogenic fashion at the N-terminus of MS2 coat protein VLPs. A VLP-based vaccine targeting HPV L2 elicits broadly cross-reactive and cross-protective antibodies to heterologous HPV types. L2-VLPs could serve as the basis of a broadly protective second generation HPV vaccine.

 

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