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Modeling of Dose-Response Relations Hips

By Altshuler, Bernard

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Book Id: WPLBN0000204469
Format Type: PDF eBook
File Size: 0.3 MB
Reproduction Date: 2005

Title: Modeling of Dose-Response Relations Hips  
Author: Altshuler, Bernard
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Publication Date:
Publisher: United Nations- Office for Disarmament Affairs (Unoda)


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Altshuler, B. (n.d.). Modeling of Dose-Response Relations Hips. Retrieved from

Government Reference Publication

Introduction: The focus of this paper is on chronic toxicity with irreversible components and in particular on cancer. It presents the more important doseresponse functions, which are of two kinds: dichotomous response and timed response. In dichotomous response, the outcome of a single animal trial is either yes, with cancer or no, without cancer; the animal is either a responder or a nonresponder. Response of an experimental group of animals is the fraction of responders.


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