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Microwaves from Gsm Mobile Telephones Affect 53Bp1 and -H2Ax Foci in Human Lymphocytes from Hypersensitive and Healthy Persons

By Persson, Bertil R. R.

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Book Id: WPLBN0000178990
Format Type: PDF eBook
File Size: 0.9 MB
Reproduction Date: 2005

Title: Microwaves from Gsm Mobile Telephones Affect 53Bp1 and -H2Ax Foci in Human Lymphocytes from Hypersensitive and Healthy Persons  
Author: Persson, Bertil R. R.
Volume:
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Historic
Publication Date:
Publisher: United Nations- Office for Disarmament Affairs (Unoda)

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R. Persso, B. R. (n.d.). Microwaves from Gsm Mobile Telephones Affect 53Bp1 and -H2Ax Foci in Human Lymphocytes from Hypersensitive and Healthy Persons. Retrieved from http://kindle.worldlibrary.net/


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Government Reference Publication

Excerpt
Excerpt: The data on biologic effects of nonthermal microwaves (MWs) from mobile telephones are diverse, and these effects are presently ignored by safety standards of the International Commission for Non- Ionizing Radiation Protection (ICNIRP). In the present study, we investigated effects of MWs of Global System for Mobile Communication (GSM) at different carrier frequencies on human lymphocytes from healthy persons and from persons reporting hypersensitivity to electromagnetic fields (EMFs). We measured the changes in chromatin conformation, which are indicative of stress response and genotoxic effects, by the method of anomalous viscosity time dependence, and we analyzed tumor suppressor p53-binding protein 1 (53BP1) and phosphorylated histone H2AX (y-H2AX), which have been shown to colocalize in distinct foci with DNA double-strand breaks (DSBs), using immunofluorescence confocal laser microscopy. We found that MWs from GSM mobile telephones affect chromatin conformation and 53BP1/y-H2AX foci similar to heat shock. For the first time, we report here that effects of MWs from mobile telephones on human lymphocytes are dependent on carrier frequency. On average, the same response was observed in lymphocytes from hypersensitive and healthy subjects. Key words: 53BP1 and y-H2AX foci, chromatin, DNA double-strand breaks, hypersensitivity to electromagnetic fields, stress response.

 

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